鬼娃再次归来，妮卡受鬼娃陷害涉嫌杀人，并疑其患有精神分裂症在精神病院治疗，鬼娃并没有放过她，而是再次在她身边犯下了一桩桩离奇、血腥、暴力、残忍的惨案，精神病院一时乱了阵脚....
在查克诅咒事件后，查克又回来了，继续恐吓坐轮椅的受害人尼卡，与此同时，这个玩具娃娃杀手在他以前妻子的帮助下，也要跟他的一些仇敌了结宿怨……
Chucky returns after the events of Curse of Chucky to continue terrorizing his wheelchair-prone human victim, Nica. Meanwhile, the killer doll has some scores to settle with his old enemies, with the help of his former wife.